1682653-80-0
1682653-80-0 structure
- Name: Tetrazine-Ph-PEG5-NHS ester
- Chemical Name: Tetrazine-PEG5-NHS ester
- CAS Number: 1682653-80-0
- Molecular Formula: C27H36N6O10
- Molecular Weight: 604.609
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-10 12:31:18
- Modify Date: 2024-01-10 11:43:58
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Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Tetrazine-PEG5-NHS ester |
|---|---|
| Synonyms |
19-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-19-oxo-N-[4-(1,2,4,5-tetrazin-3-yl)benzyl]-4,7,10,13,16-pentaoxanonadecan-1-amide
Tz-PEG5-NHS 4,7,10,13,16-Pentaoxanonadecan-1-amide, 19-[(2,5-dioxo-1-pyrrolidinyl)oxy]-19-oxo-N-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]- MFCD28505547 Tetrazine-PEG5-NHS ester |
| Description | Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C27H36N6O10 |
| Molecular Weight | 604.609 |
| Exact Mass | 604.249268 |
| LogP | -4.14 |
| Index of Refraction | 1.570 |