1802907-97-6

1802907-97-6 structure

Name: Methyltetrazine-PEG5-alkyne
Chemical Name: Methyltetrazine-PEG5-Alkyne
CAS Number: 1802907-97-6
Molecular Formula: C₂₀H₂₆N₄O₅
Molecular Weight: 402.444
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-01 10:31:51
Modify Date: 2025-08-26 20:41:38
Methyltetrazine-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methyltetrazine-PEG5-Alkyne
Synonyms	1,2,4,5-Tetrazine, 3-methyl-6-[4-(3,6,9,12-tetraoxapentadec-14-yn-1-yloxy)phenyl]- 3-Methyl-6-[4-(3,6,9,12-tetraoxapentadec-14-yn-1-yloxy)phenyl]-1,2,4,5-tetrazine MFCD28334550

Description	Methyltetrazine-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562