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1802913-21-8

1802913-21-8 structure
1802913-21-8 structure
  • Name: TCO-PEG4-acid
  • Chemical Name: TCO-PEG4-Acid
  • CAS Number: 1802913-21-8
  • Molecular Formula: C20H35NO8
  • Molecular Weight: 417.494
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-09 23:22:57
  • Modify Date: 2024-01-11 01:20:38
  • TCO-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name TCO-PEG4-Acid
Synonyms 1-[(4Z)-4-Cycloocten-1-yloxy]-1-oxo-5,8,11,14-tetraoxa-2-azaheptadecan-17-oic acid
MFCD28334565
5,8,11,14-Tetraoxa-2-azaheptadecan-17-oic acid, 1-[(4Z)-4-cycloocten-1-yloxy]-1-oxo-
Description TCO-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.

Density 1.2±0.1 g/cm3
Boiling Point 574.5±50.0 °C at 760 mmHg
Molecular Formula C20H35NO8
Molecular Weight 417.494
Flash Point 301.2±30.1 °C
Exact Mass 417.236267
LogP 1.43
Vapour Pressure 0.0±3.4 mmHg at 25°C
Index of Refraction 1.501