1807501-86-5
1807501-86-5 structure
- Name: endo-BCN-PEG4-NHS ester
- Chemical Name: endo-BCN-PEG4-NHS ester
- CAS Number: 1807501-86-5
- Molecular Formula: C26H38N2O10
- Molecular Weight: 538.587
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-12 12:12:40
- Modify Date: 2024-01-16 12:56:35
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endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | endo-BCN-PEG4-NHS ester |
|---|---|
| Synonyms |
MFCD23704191
(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate Carbamic acid, N-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-, (1R,8S)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester |
| Description | endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C26H38N2O10 |
| Molecular Weight | 538.587 |
| Exact Mass | 538.252625 |
| LogP | -0.81 |
| Index of Refraction | 1.544 |