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1807534-84-4

1807534-84-4 structure
1807534-84-4 structure
  • Name: Ald-Ph-amido-PEG2-C2-acid
  • Chemical Name: Ald--Ph-PEG2-acid
  • CAS Number: 1807534-84-4
  • Molecular Formula: C15H19NO6
  • Molecular Weight: 309.315
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-18 00:16:38
  • Modify Date: 2024-01-08 12:10:13
  • Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Ald--Ph-PEG2-acid
Synonyms ALD-PH-NH-PEG2-COOH
Description Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.2±0.1 g/cm3
Boiling Point 568.4±50.0 °C at 760 mmHg
Molecular Formula C15H19NO6
Molecular Weight 309.315
Flash Point 297.6±30.1 °C
Exact Mass 309.121246
LogP 0.17
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.554
Hazard Codes Xi