1807539-02-1
1807539-02-1 structure
- Name: Bis-PEG1-PFP ester
- Chemical Name: Bis-PEG1-PFP ester
- CAS Number: 1807539-02-1
- Molecular Formula: C18H8F10O5
- Molecular Weight: 494.237
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-07-16 18:24:44
- Modify Date: 2024-02-04 19:51:11
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Bis-PEG1-PFP ester is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Name | Bis-PEG1-PFP ester |
|---|---|
| Synonyms |
MFCD26127804
Propanoic acid, 3,3'-oxybis-, bis(2,3,4,5,6-pentafluorophenyl) ester Bis(pentafluorophenyl) 3,3'-oxydipropanoate |
| Description | Bis-PEG1-PFP ester is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
[1]. CORTEZ, Alex, et al. ANTIBODY CONJUGATES COMPRISING TOLL-LIKE RECEPTOR AGONIST. WO2017072662A1. |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 452.6±45.0 °C at 760 mmHg |
| Molecular Formula | C18H8F10O5 |
| Molecular Weight | 494.237 |
| Flash Point | 219.4±23.6 °C |
| Exact Mass | 494.021210 |
| LogP | 4.99 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.460 |