1807539-08-7

1807539-08-7 structure

Name: Bis-PEG4-sulfonic acid
Chemical Name: Bis-PEG4-sulfonic acid
CAS Number: 1807539-08-7
Molecular Formula: C₁₀H₂₂O₁₀S₂
Molecular Weight: 366.406
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-06 16:54:10
Modify Date: 2024-01-08 16:49:36
Bis-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis-PEG4-sulfonic acid
Synonyms	3,6,9,12-Tetraoxatetradecane-1,14-disulfonic acid MFCD28976669

Description	Bis-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562