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1807540-87-9

1807540-87-9 structure
1807540-87-9 structure
  • Name: Ald-Ph-amido-C2-PEG3-NH-Boc
  • Chemical Name: Ald-Ph-PEG3-NH-Boc
  • CAS Number: 1807540-87-9
  • Molecular Formula: C21H32N2O7
  • Molecular Weight: 424.488
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-22 01:11:25
  • Modify Date: 2024-01-09 15:35:51
  • Ald-Ph-amido-C2-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Ald-Ph-PEG3-NH-Boc
Synonyms ALD-PH-PEG3-NH-BOC
Description Ald-Ph-amido-C2-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.1±0.1 g/cm3
Boiling Point 614.9±55.0 °C at 760 mmHg
Molecular Formula C21H32N2O7
Molecular Weight 424.488
Flash Point 325.7±31.5 °C
Exact Mass 424.220947
LogP 1.21
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.520
Hazard Codes Xi