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1818294-39-1

1818294-39-1 structure
1818294-39-1 structure
  • Name: S-acetyl-PEG6-Boc
  • Chemical Name: S-acetyl-PEG6-t-butyl ester
  • CAS Number: 1818294-39-1
  • Molecular Formula: C21H40O9S
  • Molecular Weight: 468.602
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-14 23:57:02
  • Modify Date: 2024-01-08 18:22:37
  • S-acetyl-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name S-acetyl-PEG6-t-butyl ester
Synonyms MFCD26127816
2-Methyl-2-propanyl 2-oxo-6,9,12,15,18,21-hexaoxa-3-thiatetracosan-24-oate
6,9,12,15,18,21-Hexaoxa-3-thiatetracosan-24-oic acid, 2-oxo-, 1,1-dimethylethyl ester
Description S-acetyl-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 522.5±50.0 °C at 760 mmHg
Molecular Formula C21H40O9S
Molecular Weight 468.602
Flash Point 242.0±18.1 °C
Exact Mass 468.239288
LogP 0.44
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.471