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1818294-42-6

1818294-42-6 structure
1818294-42-6 structure
  • Name: Amino-PEG10-Boc
  • Chemical Name: Amino-PEG10-t-butyl ester
  • CAS Number: 1818294-42-6
  • Molecular Formula: C27H55NO12
  • Molecular Weight: 585.725
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-11-14 16:22:55
  • Modify Date: 2024-01-09 10:35:03
  • Amino-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Amino-PEG10-t-butyl ester
Synonyms 2-Methyl-2-propanyl 1-amino-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oate
3,6,9,12,15,18,21,24,27,30-Decaoxatritriacontan-33-oic acid, 1-amino-, 1,1-dimethylethyl ester
MFCD26127812
Description Amino-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 606.9±50.0 °C at 760 mmHg
Molecular Formula C27H55NO12
Molecular Weight 585.725
Flash Point 82.3±26.4 °C
Exact Mass 585.372437
LogP -2.38
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.462