Amino-PEG10-Boc

Modify Date: 2024-01-09 10:35:03

Amino-PEG10-Boc Structure
Amino-PEG10-Boc structure
Common Name Amino-PEG10-Boc
CAS Number 1818294-42-6 Molecular Weight 585.725
Density 1.1±0.1 g/cm3 Boiling Point 606.9±50.0 °C at 760 mmHg
Molecular Formula C27H55NO12 Melting Point N/A
MSDS N/A Flash Point 82.3±26.4 °C

 Use of Amino-PEG10-Boc


Amino-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Amino-PEG10-t-butyl ester
Synonym More Synonyms

 Amino-PEG10-Boc Biological Activity

Description Amino-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 606.9±50.0 °C at 760 mmHg
Molecular Formula C27H55NO12
Molecular Weight 585.725
Flash Point 82.3±26.4 °C
Exact Mass 585.372437
LogP -2.38
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.462

 Synonyms

2-Methyl-2-propanyl 1-amino-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oate
3,6,9,12,15,18,21,24,27,30-Decaoxatritriacontan-33-oic acid, 1-amino-, 1,1-dimethylethyl ester
MFCD26127812