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1818294-44-8

1818294-44-8 structure
1818294-44-8 structure
  • Name: Amino-PEG9-Boc
  • Chemical Name: Amino-PEG9-t-butyl ester
  • CAS Number: 1818294-44-8
  • Molecular Formula: C25H51NO11
  • Molecular Weight: 541.672
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-11-14 15:20:49
  • Modify Date: 2024-01-19 10:15:35
  • Amino-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Amino-PEG9-t-butyl ester
Synonyms 2-Methyl-2-propanyl 1-amino-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oate
3,6,9,12,15,18,21,24,27-Nonaoxatriacontan-30-oic acid, 1-amino-, 1,1-dimethylethyl ester
MFCD26127807
Description Amino-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 576.2±45.0 °C at 760 mmHg
Molecular Formula C25H51NO11
Molecular Weight 541.672
Flash Point 91.9±25.0 °C
Exact Mass 541.346191
LogP -2.02
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.461