Amino-PEG9-Boc

Modify Date: 2024-01-19 10:15:35

Amino-PEG9-Boc Structure
Amino-PEG9-Boc structure
Common Name Amino-PEG9-Boc
CAS Number 1818294-44-8 Molecular Weight 541.672
Density 1.1±0.1 g/cm3 Boiling Point 576.2±45.0 °C at 760 mmHg
Molecular Formula C25H51NO11 Melting Point N/A
MSDS N/A Flash Point 91.9±25.0 °C

 Use of Amino-PEG9-Boc


Amino-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Amino-PEG9-t-butyl ester
Synonym More Synonyms

 Amino-PEG9-Boc Biological Activity

Description Amino-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 576.2±45.0 °C at 760 mmHg
Molecular Formula C25H51NO11
Molecular Weight 541.672
Flash Point 91.9±25.0 °C
Exact Mass 541.346191
LogP -2.02
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.461

 Synonyms

2-Methyl-2-propanyl 1-amino-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oate
3,6,9,12,15,18,21,24,27-Nonaoxatriacontan-30-oic acid, 1-amino-, 1,1-dimethylethyl ester
MFCD26127807
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