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255831-16-4

255831-16-4 structure
255831-16-4 structure
  • Name: Bis-PEG3-sulfonic acid
  • Chemical Name: Bis-PEG3-sulfonic acid
  • CAS Number: 255831-16-4
  • Molecular Formula: C8H18O9S2
  • Molecular Weight: 322.353
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-23 16:18:44
  • Modify Date: 2024-01-17 10:52:36
  • Bis-PEG3-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis-PEG3-sulfonic acid
Synonyms Ethanesulfonic acid, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-
MFCD29042373
2,2'-[Oxybis(2,1-ethanediyloxy)]diethanesulfonic acid
Description Bis-PEG3-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.5±0.1 g/cm3
Molecular Formula C8H18O9S2
Molecular Weight 322.353
Exact Mass 322.039215
LogP -4.40
Index of Refraction 1.512