Bis-PEG3-sulfonic acid

Modify Date: 2024-01-17 10:52:36

Bis-PEG3-sulfonic acid Structure
Bis-PEG3-sulfonic acid structure
Common Name Bis-PEG3-sulfonic acid
CAS Number 255831-16-4 Molecular Weight 322.353
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C8H18O9S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-PEG3-sulfonic acid


Bis-PEG3-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-PEG3-sulfonic acid
Synonym More Synonyms

 Bis-PEG3-sulfonic acid Biological Activity

Description Bis-PEG3-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C8H18O9S2
Molecular Weight 322.353
Exact Mass 322.039215
LogP -4.40
Index of Refraction 1.512

 Synonyms

Ethanesulfonic acid, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-
MFCD29042373
2,2'-[Oxybis(2,1-ethanediyloxy)]diethanesulfonic acid