Name | 3-O-(2'E,4'E-Decadienoyl)ingenol |
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Synonyms |
2,4-Decadienoic acid, (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester, (2E,4E)-
(1S,4S,5S,6R,9S,10R,12R,14R)-5,6-Dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[7.5.1.01,5.010,12]pentadeca-2,7-dien-4-yl (2E,4E)-2,4-decadienoate |
Description | 3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC50s of 8.22 μM and 6.67 μM, respectively[1]. |
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Related Catalog | |
In Vitro | 3-O-(2'E,4'E-Decadienoyl)-ingenol(5-30 μg/mL;24 小时)显示出对人类正常细胞系 L-O2 和 GES-1 的细胞毒性,具有剂量依赖关系 [1]。 Cell Cytotoxicity Assay[1] Cell Line: L-O2 and GES-1 cells Concentration: 5 μg/mL, 10 μg/mL,15 μg/mL, 20 μg/mL, 25 μg/mL, 30 μg/mL Incubation Time: 24 hours Result: Showed cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 635.6±55.0 °C at 760 mmHg |
Molecular Formula | C30H42O6 |
Molecular Weight | 498.651 |
Flash Point | 201.7±25.0 °C |
Exact Mass | 498.298126 |
LogP | 7.30 |
Vapour Pressure | 0.0±4.2 mmHg at 25°C |
Index of Refraction | 1.584 |