488150-84-1

488150-84-1 structure
488150-84-1 structure
  • Name: Propargyl-PEG1-Boc
  • Chemical Name: Propargyl-PEG1-t-butyl ester
  • CAS Number: 488150-84-1
  • Molecular Formula: C10H16O3
  • Molecular Weight: 184.232
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-19 09:50:39
  • Modify Date: 2025-08-25 20:00:44
  • Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG1-t-butyl ester
Synonyms PROPARGYL-PEG1-CH2CH2COOTBU
Description Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.0±0.1 g/cm3
Boiling Point 239.2±15.0 °C at 760 mmHg
Molecular Formula C10H16O3
Molecular Weight 184.232
Flash Point 93.1±15.0 °C
Exact Mass 184.109940
LogP 1.97
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.443
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