Propargyl-PEG1-Boc

Modify Date: 2025-08-25 20:00:44

Propargyl-PEG1-Boc Structure
Propargyl-PEG1-Boc structure
Common Name Propargyl-PEG1-Boc
CAS Number 488150-84-1 Molecular Weight 184.232
Density 1.0±0.1 g/cm3 Boiling Point 239.2±15.0 °C at 760 mmHg
Molecular Formula C10H16O3 Melting Point N/A
MSDS N/A Flash Point 93.1±15.0 °C

 Use of Propargyl-PEG1-Boc


Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG1-t-butyl ester
Synonym More Synonyms

 Propargyl-PEG1-Boc Biological Activity

Description Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 239.2±15.0 °C at 760 mmHg
Molecular Formula C10H16O3
Molecular Weight 184.232
Flash Point 93.1±15.0 °C
Exact Mass 184.109940
LogP 1.97
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.443

 Synonyms

PROPARGYL-PEG1-CH2CH2COOTBU
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