944548-38-3

944548-38-3 structure

944548-38-3 structure

Name: Foravirumab
Chemical Name: Foravirumab
CAS Number: 944548-38-3
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Infection
Create Date: 2018-12-03 22:04:43
Modify Date: 2023-02-04 19:23:46
Foravirumab (CR4098) is a monoclonal antibody against rabies virus glycoprotein antigenic site III[1].

Name	Foravirumab

Description	Foravirumab (CR4098) is a monoclonal antibody against rabies virus glycoprotein antigenic site III[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
In Vitro	Foravirumab (CR4098) recognizes epitopes localized in antigenic site III. Foravirumab still binds to the mutated glycoprotein (N336D) expressed on PER.C6 cells. Foravirumab shows similar neutralizing potency and breadth as CR57, and neutralizes CR57 escape mutants[1].
In Vivo	In Syrian hamster bearing natural rabies virus, Foravirumab (CR4098; 10, 20, and 40 IU/kg) provids protection against the lethal natural rabies virus infection[1].
References	[1]. Alexander B H Bakker, et al. Novel human monoclonal antibody combination effectively neutralizing natural rabies virus variants and individual in vitro escape mutants. J Virol. 2005 Jul;79(14):9062-8.

No Any Chemical & Physical Properties