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1599440-13-7

1599440-13-7 structure
1599440-13-7 structure

Name Deruxtecan analog
Description Deruxtecan analog is a drug-linker conjugate for antibody-drug conjugate (ADC) extracted from patent WO2017002776A1, compound 1.
Related Catalog
Target

Drug-linker conjugates for ADC[1]

In Vitro Antibody-drug conjugates deliver anticancer agents selectively and efficiently to tumor tissue and have significant antitumor efficacy with a wide therapeutic window[2].
References

[1]. NOGUCHI, Shigeru, et al. METHOD FOR SELECTIVELY MANUFACTURING ANTIBODY-DRUG CONJUGATE. WO2017002776A1.

[2]. Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.

Density 1.48±0.1 g/cm3
Boiling Point 1491.1±65.0 °C
Molecular Formula C52H56FN9O13
Molecular Weight 1034.05
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