2138299-34-8

2138299-34-8 structure
2138299-34-8 structure

Name diABZI STING agonist-1 trihydrochloride
Description diABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist.
Related Catalog
Target

STING[1].

In Vivo diABZI STING agonist-1 (trihydrochloride) activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting−/− mice, confirming that diABZI STING agonist-1 (trihydrochloride) STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].
References

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.

Molecular Formula C42H54Cl3N13O7
Molecular Weight 959.32
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