1357362-02-7
1357362-02-7 structure
- Name: Vafidemstat
- Chemical Name: Vafidemstat
- CAS Number: 1357362-02-7
- Molecular Formula: C19H20N4O2
- Molecular Weight: 336.39
- Catalog: Signaling Pathways Epigenetics Histone Demethylase
- Create Date: 2019-02-12 09:53:27
- Modify Date: 2025-08-25 18:15:55
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Vafidemstat is a dual lysine-specific histone demethylase (LSD1)/MAO-B inhibitor.
| Name | Vafidemstat |
|---|
| Description | Vafidemstat is a dual lysine-specific histone demethylase (LSD1)/MAO-B inhibitor. |
|---|---|
| Related Catalog | |
| Target |
LSD1/MAO-B[1] |
| In Vitro | Vafidemstat (ORY-2001), a dual LSD1/MAO-B inhibitor, is a novel epigenetic agent for the treatment of neurodegenerative diseases. LSD1 is a protein that participates in transcription regulation complexes; its modulation can be used to tweak transcriptional imbalances in neurodegenerative disease and redress neuroinflammation and cognitive deficit[1]. Vafidemstat (ORY-2001) can be used in the treatment of Alzheimer's disease[2]. |
| References |
[2]. ORYZON Reports Financial Results and Corporate Update for the 1st Half Ended June 30, 2018. |
| Molecular Formula | C19H20N4O2 |
|---|---|
| Molecular Weight | 336.39 |