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2088518-50-5

2088518-50-5 structure
2088518-50-5 structure
  • Name: Dot1L-IN-1
  • Chemical Name: Dot1L-IN-1
  • CAS Number: 2088518-50-5
  • Molecular Formula: C32H36ClN9O2S
  • Molecular Weight: 646.21
  • Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
  • Create Date: 2019-03-03 12:58:09
  • Modify Date: 2024-01-09 13:09:26
  • Dot1L-IN-1 is a highly potent, selective and structurally novel Dot1L inhibitor with a Ki of 2 pM.

Name Dot1L-IN-1
Description Dot1L-IN-1 is a highly potent, selective and structurally novel Dot1L inhibitor with a Ki of 2 pM.
Related Catalog
Target

Ki: 2 pM (Dot1L)[1]

References

[1]. Möbitz H, et al. Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach. ACS Med Chem Lett. 2017 Feb 14;8(3):338-343.

Molecular Formula C32H36ClN9O2S
Molecular Weight 646.21
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