1467157-21-6

1467157-21-6 structure

Name: Durlobactam sodium salt
Chemical Name: Durlobactam sodium salt
CAS Number: 1467157-21-6
Molecular Formula: C₈H₁₀N₃NaO₆S
Molecular Weight: 299.24
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2019-03-04 07:21:10
Modify Date: 2024-01-02 04:49:17
Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii[1].

Name	Durlobactam sodium salt

Description	Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 4 nM (Class A KPC-2), 14 nM (Class C AmpC), 190 nM (Class D OXA-24)[1].
References	[1]. Durand-Réville TF, et al. ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Nat Microbiol. 2017 Jun 30;2:17104.

Molecular Formula	C₈H₁₀N₃NaO₆S
Molecular Weight	299.24