Durlobactam sodium salt

Modify Date: 2024-01-02 04:49:17

Durlobactam sodium salt Structure
Durlobactam sodium salt structure
Common Name Durlobactam sodium salt
CAS Number 1467157-21-6 Molecular Weight 299.24
Density N/A Boiling Point N/A
Molecular Formula C8H10N3NaO6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Durlobactam sodium salt


Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii[1].

 Names

Name Durlobactam sodium salt

 Durlobactam sodium salt Biological Activity

Description Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii[1].
Related Catalog
Target

IC50: 4 nM (Class A KPC-2), 14 nM (Class C AmpC), 190 nM (Class D OXA-24)[1].

References

[1]. Durand-Réville TF, et al. ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Nat Microbiol. 2017 Jun 30;2:17104.

 Chemical & Physical Properties

Molecular Formula C8H10N3NaO6S
Molecular Weight 299.24
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