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  • DC Chemicals Limited
  • China
  • Product Name: BAY-293
  • Price: $750.0/100mg $1300.0/250mg $2500.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

2244904-70-7

2244904-70-7 structure
2244904-70-7 structure
  • Name: BAY 293
  • Chemical Name: BAY-293
  • CAS Number: 2244904-70-7
  • Molecular Formula: C25H28N4O2S
  • Molecular Weight: 448.58
  • Catalog: Research Areas Cancer
  • Create Date: 2019-03-30 17:21:34
  • Modify Date: 2024-01-18 18:44:20
  • BAY-293 is a potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction with an IC50 of 21 nM[1].

Name BAY-293
Description BAY-293 is a potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction with an IC50 of 21 nM[1].
Related Catalog
Target

IC50: 21 nM (KRAS-SOS1 interaction)[1]

References

[1]. Hillig RC, et al. Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1interaction. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2551-2560.

Molecular Formula C25H28N4O2S
Molecular Weight 448.58