BAY 293

Modify Date: 2024-01-18 18:44:20

BAY 293 Structure
BAY 293 structure
Common Name BAY 293
CAS Number 2244904-70-7 Molecular Weight 448.58
Density N/A Boiling Point N/A
Molecular Formula C25H28N4O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BAY 293


BAY-293 is a potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction with an IC50 of 21 nM[1].

 Names

Name BAY-293

 BAY 293 Biological Activity

Description BAY-293 is a potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction with an IC50 of 21 nM[1].
Related Catalog
Target

IC50: 21 nM (KRAS-SOS1 interaction)[1]

References

[1]. Hillig RC, et al. Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1interaction. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2551-2560.

 Chemical & Physical Properties

Molecular Formula C25H28N4O2S
Molecular Weight 448.58