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874590-32-6

874590-32-6 structure
874590-32-6 structure
  • Name: M1001
  • Chemical Name: M1001
  • CAS Number: 874590-32-6
  • Molecular Formula: C17H17N3O2S
  • Molecular Weight: 327.40
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease HIF/HIF Prolyl-Hydroxylase
  • Create Date: 2019-03-30 13:14:34
  • Modify Date: 2025-08-25 17:36:28
  • M1001 is a weak agonist of HIF-2α, directly binds to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 enhances the stabilities of HIF-2α-ARNT complex[1].

Name M1001
Description M1001 is a weak agonist of HIF-2α, directly binds to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 enhances the stabilities of HIF-2α-ARNT complex[1].
Related Catalog
Target

Kd: 667 nM (HIF-2α)[1]

References

[1]. Wu D, et al. Bidirectional modulation of HIF-2 activity through chemical ligands. Nat Chem Biol. 2019 Feb 25.

Molecular Formula C17H17N3O2S
Molecular Weight 327.40
Storage condition 2-8°C
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