2219323-96-1

2219323-96-1 structure

Name: mTOR Inhibitor 1
Chemical Name: mTOR Inhibitor 1
CAS Number: 2219323-96-1
Molecular Formula: C₂₃H₂₁N₇O
Molecular Weight: 411.46
Catalog: Signaling Pathways PI3K/Akt/mTOR mTOR
Create Date: 2019-03-30 19:59:33
Modify Date: 2024-01-16 10:17:59
mTOR Inhibitor 1 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR Inhibitor 1 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].

Name	mTOR Inhibitor 1

Description	mTOR Inhibitor 1 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR Inhibitor 1 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Research Areas >> Cancer
Target	mTOR:7 nM (IC50)
References	[1]. Guo Q, et al. Highly Selective, Potent, and Oral mTOR Inhibitor for Treatment of Cancer as Autophagy Inducer. J Med Chem. 2018 Feb 8;61(3):881-904.

Molecular Formula	C₂₃H₂₁N₇O
Molecular Weight	411.46