mTOR Inhibitor 1

Modify Date: 2024-01-16 10:17:59

mTOR Inhibitor 1 structure	Common Name	mTOR Inhibitor 1
	CAS Number	2219323-96-1	Molecular Weight	411.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₁N₇O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of mTOR Inhibitor 1

mTOR Inhibitor 1 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR Inhibitor 1 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].

Name	mTOR Inhibitor 1

Description	mTOR Inhibitor 1 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR Inhibitor 1 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Research Areas >> Cancer
Target	mTOR:7 nM (IC50)
References	[1]. Guo Q, et al. Highly Selective, Potent, and Oral mTOR Inhibitor for Treatment of Cancer as Autophagy Inducer. J Med Chem. 2018 Feb 8;61(3):881-904.

Molecular Formula	C₂₃H₂₁N₇O
Molecular Weight	411.46