1984825-08-2

1984825-08-2 structure

1984825-08-2 structure

Name: TRPA1 Antagonist 1
Chemical Name: TRPA1 Antagonist 1
CAS Number: 1984825-08-2
Molecular Formula: C₂₄H₂₀F₆N₅Na₂O₇PS
Molecular Weight: 713.45
Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
Create Date: 2019-03-30 12:13:33
Modify Date: 2024-01-07 21:06:42
TRPA1 Antagonist 1 is a methylene phosphate prodrug which converts to its active parent drug, a TRPA1 antagonist with an IC50 of 8 nM.

Name	TRPA1 Antagonist 1

Description	TRPA1 Antagonist 1 is a methylene phosphate prodrug which converts to its active parent drug, a TRPA1 antagonist with an IC50 of 8 nM.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Neurological Disease
Target	IC50: 8 nM (TRPA1)[1]
References	[1]. Chen H, et al. Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling. J Med Chem. 2018 Apr 26;61(8):3641-3659.

Molecular Formula	C₂₄H₂₀F₆N₅Na₂O₇PS
Molecular Weight	713.45