TRPA1 Antagonist 1

Modify Date: 2025-09-18 20:01:34

TRPA1 Antagonist 1 structure	Common Name	TRPA1 Antagonist 1
	CAS Number	1984825-08-2	Molecular Weight	713.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₀F₆N₅Na₂O₇PS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TRPA1 Antagonist 1

TRPA1 Antagonist 1 is a methylene phosphate prodrug which converts to its active parent drug, a TRPA1 antagonist with an IC50 of 8 nM.

Name	TRPA1 Antagonist 1

Description	TRPA1 Antagonist 1 is a methylene phosphate prodrug which converts to its active parent drug, a TRPA1 antagonist with an IC50 of 8 nM.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Neurological Disease
Target	IC50: 8 nM (TRPA1)[1]
References	[1]. Chen H, et al. Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling. J Med Chem. 2018 Apr 26;61(8):3641-3659.

Molecular Formula	C₂₄H₂₀F₆N₅Na₂O₇PS
Molecular Weight	713.45
InChIKey	NYXRQEACCSRRHX-IFUMFIRSSA-N
SMILES	CC1C(F)CC(C(=O)N(COP(=O)(O)O)Cc2cc(-c3cnc(C(F)(F)F)nc3)ncc2F)N1S(=O)(=O)c1ccc(F)cc1.[Na].[Na]

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TRPA1 Antagonist 1
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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