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1700637-55-3

1700637-55-3 structure
1700637-55-3 structure
  • Name: CD38 inhibitor 78c
  • Chemical Name: CD38 inhibitor 1
  • CAS Number: 1700637-55-3
  • Molecular Formula: C22H27N3O3S
  • Molecular Weight: 413.53
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2019-06-01 14:01:48
  • Modify Date: 2024-01-04 20:18:26
  • CD38 inhibitor 1 is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for human and mouse, respectively[1].

Name CD38 inhibitor 1
Description CD38 inhibitor 1 is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for human and mouse, respectively[1].
Related Catalog
In Vivo CD38 inhibitor (30 mg/kg; oral administration; 2 and 6 hours) significantly elevates NAD levels in liver and muscle[1]. Animal Model: Diet induced obese (DIO) C57Bl6 mice[1] Dosage: 30 mg/kg Administration: Orally once Result: NAD levels were significantly increased at both the 2 and 6 h time points in liver and muscle.
References

[1]. Haffner CD, et al. Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors. J Med Chem. 2015 Apr 23;58(8):3548-71.

Molecular Formula C22H27N3O3S
Molecular Weight 413.53
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