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332164-34-8

332164-34-8 structure

332164-34-8 structure

Name: HFI-142
Chemical Name: HFI-142
CAS Number: 332164-34-8
Molecular Formula: C₁₇H₁₆N₂O₄
Molecular Weight: 312.32
Catalog: Signaling Pathways Metabolic Enzyme/Protease Aminopeptidase
Create Date: 2019-07-10 14:56:18
Modify Date: 2026-07-01 08:40:54
HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor with a ki of 2.01 μM[1].

Name	HFI-142
Synonyms	Ethyl 2-amino-7-hydroxy-4-(3-pyridinyl)-4H-1-benzopyran-3-cboxylate 4H-1-Benzopyran-3-cboxylic acid, 2-amino-7-hydroxy-4-(3-pyridinyl)-, ethyl ester Ethyl 2-amino-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-cboxylate HFI 142,HFI

Description	HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor with a ki of 2.01 μM[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Aminopeptidase Research Areas >> Neurological Disease
Target	ki: 2.01 μM (Insulin-regulated aminopeptidase)[1]
References	[1]. Albiston AL, et al. Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobicpacking point at the active site of insulin-regulated aminopeptidase. Mol Pharmacol. 2010 Oct;78(4):600-7.

Molecular Formula	C₁₇H₁₆N₂O₄
Molecular Weight	312.32

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