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1584647-27-7

1584647-27-7 structure
1584647-27-7 structure
  • Name: BMS-986115
  • Chemical Name: Notch inhibitor 1
  • CAS Number: 1584647-27-7
  • Molecular Formula: C26H25F7N4O3
  • Molecular Weight: 574.49
  • Catalog: Signaling Pathways Stem Cell/Wnt Notch
  • Create Date: 2019-06-01 23:16:02
  • Modify Date: 2025-08-26 10:37:31
  • Notch inhibitor 1 is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer[1].

Name Notch inhibitor 1
Description Notch inhibitor 1 is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer[1].
Related Catalog
Target

IC50: 7.8 nM (Notch 1), 8.5 nM (Notch 3)[1]

In Vitro Notch inhibitor 1 (Example 1) potently inhibits Notch signaling pathway[1].
References

[1]. Ashvinikumar V. Gavai, et al. Bis(fluoroalkyl)-1,4-benzodiazepinone compounds as notch inhibitors. WO2014047372A1.

Molecular Formula C26H25F7N4O3
Molecular Weight 574.49
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