2113688-43-8
2113688-43-8 structure
- Name: SNIPER(AR)-51
- Chemical Name: SNIPER(AR)-51
- CAS Number: 2113688-43-8
- Molecular Formula: C55H65N7O8S
- Molecular Weight: 984.21
- Catalog: Research Areas Cancer
- Create Date: 2019-06-02 08:45:44
- Modify Date: 2025-08-25 18:29:20
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SNIPER(AR)-51 (AR-51), consists of a cIAP1 ligand and an androgen ligand, connected by a linker[1]. SNIPER(AR)-51 induces androgen receptor (AR) protein degradation[1].
| Name | SNIPER(AR)-51 |
|---|
| Description | SNIPER(AR)-51 (AR-51), consists of a cIAP1 ligand and an androgen ligand, connected by a linker[1]. SNIPER(AR)-51 induces androgen receptor (AR) protein degradation[1]. |
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| Related Catalog | |
| In Vitro | SNIPER(AR)-51 (3 μM; 24 hours) exhibits a pronounced effect on the cell morphology of VCaP cells to induce apoptosis[1]. SNIPER(AR)-51 (3 μM; 24 hours) induces caspase-3 activation and PARP cleavage in prostate cancer VCaP cells[1]. Apoptosis Analysis[1] Cell Line: Prostate cancer VCaP cells Concentration: 3 μM Incubation Time: 24 hours Result: Induced apoptosis. Western Blot Analysis[1] Cell Line: VCaP cells Concentration: 1 μM and 3 μM Incubation Time: 24 hours Result: Induced caspase-3 activation and PARP cleavage at 3 μM. |
| References |
| Molecular Formula | C55H65N7O8S |
|---|---|
| Molecular Weight | 984.21 |