1637542-32-5

1637542-32-5 structure
1637542-32-5 structure
  • Name: (R)-Nedisertib
  • Chemical Name: (R)-Nedisertib
  • CAS Number: 1637542-32-5
  • Molecular Formula: C24H21ClFN5O3
  • Molecular Weight: 481.91
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA-PK
  • Create Date: 2019-06-01 18:10:44
  • Modify Date: 2024-01-09 18:43:33
  • (R)-Nedisertib ((R)-M3814) is a less active R-enantiomer of Nedisertib, with an IC50 in the range of 7-30 nM for DNA-PK[1].

Name (R)-Nedisertib
Description (R)-Nedisertib ((R)-M3814) is a less active R-enantiomer of Nedisertib, with an IC50 in the range of 7-30 nM for DNA-PK[1].
Related Catalog
Target

DNA-PK:7-30 nM (IC50)

In Vitro Rac-Nedisertib (Compound 135) less actively inhibits DNA-PK, with an IC50 in the range of 7-30 nM[1].
References

[1]. Thomas Fuchss, et al. Arylchinazoline. WO2014183850A1.

Molecular Formula C24H21ClFN5O3
Molecular Weight 481.91
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