(R)-Nedisertib

Modify Date: 2024-01-09 18:43:33

(R)-Nedisertib Structure
(R)-Nedisertib structure
Common Name (R)-Nedisertib
CAS Number 1637542-32-5 Molecular Weight 481.91
Density N/A Boiling Point N/A
Molecular Formula C24H21ClFN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-Nedisertib


(R)-Nedisertib ((R)-M3814) is a less active R-enantiomer of Nedisertib, with an IC50 in the range of 7-30 nM for DNA-PK[1].

 Names

Name (R)-Nedisertib

 (R)-Nedisertib Biological Activity

Description (R)-Nedisertib ((R)-M3814) is a less active R-enantiomer of Nedisertib, with an IC50 in the range of 7-30 nM for DNA-PK[1].
Related Catalog
Target

DNA-PK:7-30 nM (IC50)

In Vitro Rac-Nedisertib (Compound 135) less actively inhibits DNA-PK, with an IC50 in the range of 7-30 nM[1].
References

[1]. Thomas Fuchss, et al. Arylchinazoline. WO2014183850A1.

 Chemical & Physical Properties

Molecular Formula C24H21ClFN5O3
Molecular Weight 481.91
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