52580-29-7

52580-29-7 structure

Name: Angiotensin II (1-4), human
Chemical Name: Angiotensin II (1-4), human
CAS Number: 52580-29-7
Molecular Formula: C₂₄H₃₇N₇O₈
Molecular Weight: 551.59
Catalog: Signaling Pathways GPCR/G Protein Angiotensin Receptor
Create Date: 2019-06-29 12:21:05
Modify Date: 2025-08-25 10:23:39
Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[1][2].

Name	Angiotensin II (1-4), human

Description	Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor Research Areas >> Metabolic Disease
References	[1]. De Giusti VC, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. [2]. Moon JY, et al. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-5.

Molecular Formula	C₂₄H₃₇N₇O₈
Molecular Weight	551.59