1217471-51-6

1217471-51-6 structure

Name: FTI 276 TFA
Chemical Name: FTI 276 TFA
CAS Number: 1217471-51-6
Molecular Formula: C₂₃H₂₈F₃N₃O₅S₂
Molecular Weight: 547.61
Catalog: Signaling Pathways Metabolic Enzyme/Protease Farnesyl Transferase
Create Date: 2019-06-30 11:41:15
Modify Date: 2024-01-06 21:18:56
FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 nM and 0.5 nM for Plasmodium falciparum and human, respectively[1].

Name	FTI 276 TFA

Description	FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 nM and 0.5 nM for Plasmodium falciparum and human, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Farnesyl Transferase
Target	IC50: 0.9 nM (PFT, Plasmodium falciparum), 0.5 nM (PFT, human)[1].
References	[1]. Chakrabarti D, et al. Protein farnesyltransferase and protein prenylation in Plasmodium falciparum.J Biol Chem. 2002 Nov 1; 277(44):42066-73. Epub 2002 Aug 22.