2143475-98-1

2143475-98-1 structure

Name: GeA-69
Chemical Name: GeA-69
CAS Number: 2143475-98-1
Molecular Formula: C₂₀H₁₆N₂O
Molecular Weight: 300.35
Catalog: Signaling Pathways Cell Cycle/DNA Damage PARP
Create Date: 2019-06-29 15:55:05
Modify Date: 2024-01-14 16:41:46
GeA-69 is a selective, highly cell permeable allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2, with a Kd of 2.1 µM[1].

Name	GeA-69

Description	GeA-69 is a selective, highly cell permeable allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2, with a Kd of 2.1 µM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	PARP14:2.1 μM (Kd)
References	[1]. Schuller M, et al. Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14. ACS Chem Biol. 2017 Nov 17;12(11):2866-2874.