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1642581-63-2

1642581-63-2 structure
1642581-63-2 structure
  • Name: Glumetinib
  • Chemical Name: Glumetinib
  • CAS Number: 1642581-63-2
  • Molecular Formula: C21H17N9O2S
  • Molecular Weight: 459.48
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK c-Met/HGFR
  • Create Date: 2019-06-30 16:39:15
  • Modify Date: 2024-01-10 18:00:47
  • Glumetinib (SCC244) is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin[1].

Name Glumetinib
Description Glumetinib (SCC244) is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin[1].
Related Catalog
Target

IC50: 0.42 nM (c-Met kinase)[1]

References

[1]. Ai J, et al. Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective Inhibitor of c-Met in MET-dependent Cancer Models. Mol Cancer Ther. 2018 Apr;17(4):751-762.

Molecular Formula C21H17N9O2S
Molecular Weight 459.48
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