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1953157-39-5

1953157-39-5 structure
1953157-39-5 structure
  • Name: GSK 366
  • Chemical Name: GSK 366
  • CAS Number: 1953157-39-5
  • Molecular Formula: C17H16ClN3O4
  • Molecular Weight: 361.78
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2019-06-30 18:15:15
  • Modify Date: 2024-01-10 16:49:56
  • GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50s of 2.3 nM and 0.7 nM for human KMO and P. fluorescens-KMO (Pf-KMO), respectively [1].
Name GSK 366
Description GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50s of 2.3 nM and 0.7 nM for human KMO and P. fluorescens-KMO (Pf-KMO), respectively [1].
Related Catalog
Target

IC50: 2.3 nM (human KMO), 0.7 nM (Pf-KMO)[1]

References

[1]. Hutchinson JP, et al. Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase. Nat Commun. 2017 Jun 12;8:15827.
Molecular Formula C17H16ClN3O4
Molecular Weight 361.78
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