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1628332-52-4

1628332-52-4 structure
1628332-52-4 structure
  • Name: cGAS inhibitor 467
  • Chemical Name: GSK467
  • CAS Number: 1628332-52-4
  • Molecular Formula: C17H13N5O2
  • Molecular Weight: 319.32
  • Catalog: Signaling Pathways Epigenetics Histone Demethylase
  • Create Date: 2019-06-30 05:32:05
  • Modify Date: 2024-01-08 16:18:44
  • GSK467 is a selective KDM5 (JARID1) inhibitor with a Ki of 10 nM for KDM5B, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other Jumonji family members[1].

Name GSK467
Description GSK467 is a selective KDM5 (JARID1) inhibitor with a Ki of 10 nM for KDM5B, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other Jumonji family members[1].
Related Catalog
Target

Ki: 10 nM (KDM5B)[1]

References

[1]. Johansson C, et al. Structural analysis of human KDM5B guides histone demethylase inhibitor development. Nat Chem Biol. 2016 Jul;12(7):539-45.

Molecular Formula C17H13N5O2
Molecular Weight 319.32
Storage condition 2-8℃