1494585-79-3

1494585-79-3 structure
1494585-79-3 structure
  • Name: NaV1.7 inhibitor-1
  • Chemical Name: NaV1.7 inhibitor-1
  • CAS Number: 1494585-79-3
  • Molecular Formula: C23H30FNO4S
  • Molecular Weight: 435.55
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
  • Create Date: 2019-06-30 09:36:15
  • Modify Date: 2024-04-05 00:33:33
  • NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5[1].

Name NaV1.7 inhibitor-1
Description NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5[1].
Related Catalog
Target

IC50: 0.6 nM (hNaV1.7)[1]

References

[1]. Sun S, Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-GatedSodium Channel (NaV) 1.7 with Potent Analgesic Activity. J Med Chem. 2019 Jan 24;62(2):908-927.

Molecular Formula C23H30FNO4S
Molecular Weight 435.55
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