2230826-81-8

2230826-81-8 structure

Name: PROTAC FLT-3 degrader 1
Chemical Name: PROTAC FLT-3 degrader 1
CAS Number: 2230826-81-8
Molecular Formula: C₅₂H₆₁N₉O₉S₂
Molecular Weight: 1020.23
Catalog: Signaling Pathways PROTAC PROTAC
Create Date: 2019-06-29 13:27:05
Modify Date: 2024-01-09 21:27:12
PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1].

Name	PROTAC FLT-3 degrader 1

Description	PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC
Target	IC50: 0.6 nM (FLT-3 ITD)[1]
References	[1]. Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140(48):16428-16432.