PROTAC FLT-3 degrader 1

Modify Date: 2024-01-09 21:27:12

PROTAC FLT-3 degrader 1 structure	Common Name	PROTAC FLT-3 degrader 1
	CAS Number	2230826-81-8	Molecular Weight	1020.23
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₂H₆₁N₉O₉S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC FLT-3 degrader 1

PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1].

Name	PROTAC FLT-3 degrader 1

Description	PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC
Target	IC50: 0.6 nM (FLT-3 ITD)[1]
References	[1]. Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140(48):16428-16432.

Molecular Formula	C₅₂H₆₁N₉O₉S₂
Molecular Weight	1020.23
Storage condition	-20°C