1848959-11-4

1848959-11-4 structure
1848959-11-4 structure

Name TAS4464 hydrochloride
Synonyms MFCD32067968
Description TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1].
Related Catalog
Target

IC50:0.955 nM (NAE)[1]

References

[1]. Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.

Molecular Formula C21H24ClFN6O6S
Molecular Weight 542.97