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2095280-64-9

2095280-64-9 structure
2095280-64-9 structure
  • Name: Chmfl-btk-01
  • Chemical Name: CHMFL-BTK-01
  • CAS Number: 2095280-64-9
  • Molecular Formula: C38H41N5O5
  • Molecular Weight: 647.76
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Btk
  • Create Date: 2019-08-04 12:46:59
  • Modify Date: 2024-01-10 18:25:09
  • CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation[1].

Name CHMFL-BTK-01
Description CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation[1].
Related Catalog
Target

IC50: 7 nM (BTK)[1].

References

[1]. Liang Q, et al. Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor. Eur J Med Chem. 2017 May 5;131:107-125.

Molecular Formula C38H41N5O5
Molecular Weight 647.76