Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CHMFL-BTK-01
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Chmfl-btk-01
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2095280-64-9

2095280-64-9 structure

2095280-64-9 structure

Name: Chmfl-btk-01
Chemical Name: CHMFL-BTK-01
CAS Number: 2095280-64-9
Molecular Formula: C₃₈H₄₁N₅O₅
Molecular Weight: 647.76
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Btk
Create Date: 2019-08-04 12:46:59
Modify Date: 2024-01-10 18:25:09
CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation[1].

Name	CHMFL-BTK-01

Description	CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
Target	IC50: 7 nM (BTK)[1].
References	[1]. Liang Q, et al. Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor. Eur J Med Chem. 2017 May 5;131:107-125.

Molecular Formula	C₃₈H₄₁N₅O₅
Molecular Weight	647.76

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