Chmfl-btk-01

Modify Date: 2024-01-10 18:25:09

Chmfl-btk-01 Structure
Chmfl-btk-01 structure
Common Name Chmfl-btk-01
CAS Number 2095280-64-9 Molecular Weight 647.76
Density N/A Boiling Point N/A
Molecular Formula C38H41N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Chmfl-btk-01


CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation[1].

 Names

Name CHMFL-BTK-01

 Chmfl-btk-01 Biological Activity

Description CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation[1].
Related Catalog
Target

IC50: 7 nM (BTK)[1].

References

[1]. Liang Q, et al. Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor. Eur J Med Chem. 2017 May 5;131:107-125.

 Chemical & Physical Properties

Molecular Formula C38H41N5O5
Molecular Weight 647.76
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